SAMtools

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Introduction

Samtools is a suite of programs for interacting with high-throughput sequencing data. It consists of three separate repositories:

  • Samtools - Reading/writing/editing/indexing/viewing SAM/BAM/CRAM format
  • BCFtools - Reading/writing BCF2/VCF/gVCF files and calling/filtering/summarising SNP and short indel sequence variants
  • HTSlib - A C library for reading/writing high-throughput sequencing data

Samtools and BCFtools both use HTSlib internally, but these source packages contain their own copies of htslib so they can be built independently.

Installed Version

The currently installed version is 1.3.1.

Using SAMtools on the HPC cluster

Documentation

The full documentation can be found here.